2-(4-methylphenoxymethyl)benzoyl isothiocyanate

Base Information

• Chemical Name: 2-(4-methylphenoxymethyl)benzoyl isothiocyanate
• CAS No.: 1410888-73-1
• Molecular Formula: C₁₆H₁₃NO₂S
• Molecular Weight: 283.351
• Mol file: 1410888-73-1.mol

Synonyms:

Chemical Property of 2-(4-methylphenoxymethyl)benzoyl isothiocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methylphenoxymethyl)benzoyl isothiocyanate

There total 3 articles about 2-(4-methylphenoxymethyl)benzoyl isothiocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzofuran-1(3H)-one (87-41-2) → 2-(4-methylphenoxymethyl)benzoyl isothiocyanate (1410888-73-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene

1.2: Reflux

2.1: thionyl chloride / 1,2-dichloro-ethane

3.1: acetone / 1 h / Reflux

With thionyl chloride; potassium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; 1,2-dichloro-ethane; acetone;

DOI:10.3390/molecules16097593

Reference yield:

p-cresol (106-44-5) → 2-(4-methylphenoxymethyl)benzoyl isothiocyanate (1410888-73-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene

1.2: Reflux

2.1: thionyl chloride / 1,2-dichloro-ethane

3.1: acetone / 1 h / Reflux

With thionyl chloride; potassium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene; 1,2-dichloro-ethane; acetone;

DOI:10.3390/molecules16097593

Reference yield:

ammonium thiocyanate (1147550-11-5) + 2-((4-methylphenoxy)methyl)benzoyl chloride (1015048-47-1) → 2-(4-methylphenoxymethyl)benzoyl isothiocyanate (1410888-73-1)

Guidance literature:

In acetone; for 1h; Reflux;

upstream raw materials:

ammonium thiocyanate

2-((4-methylphenoxy)methyl)benzoyl chloride

2-benzofuran-1(3H)-one

p-cresol

Downstream raw materials:

2-((4-methylphenoxy)methyl)-N-((3-fluorophenyl)carbamothioyl)benzamide

2-((4-methylphenoxy)methyl)-N-((2,5-dibromophenyl)carbamothioyl)benzamide

2-((4-methylphenoxy)methyl)-N-((2,4,5-trifluorophenyl)carbamothioyl)benzamide

2-((4-methylphenoxy)methyl)-N-((2-iodophenyl)carbamothioyl)benzamide