3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione

Base Information

Chemical Name:3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione
CAS No.:1449294-66-9
Molecular Formula:C₁₄H₇F₃N₂O₂
Molecular Weight:292.217
Hs Code.:

Synonyms:

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Chemical Property of 3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione

Chemical Property:

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Technology Process of 3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione

There total 3 articles about 3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₁₁F₃N₂O₃

: 1449294-66-9
3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione

Guidance literature:: With sodium hydroxide; In ethanol; at 80 ℃; for 0.5h;
DOI:10.3987/COM-12-S(N)109

Reference yield:

: 50528-80-8
1,3,5-trifluoro-2-isocyanatobenzene

: 1449294-66-9
3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 2 h / Reflux

2: sodium hydroxide / ethanol / 0.5 h / 80 °C

With sodium hydroxide; In ethanol; toluene;
DOI:10.3987/COM-12-S(N)109

Reference yield:

: 363-81-5
2,4,6-trifluoroaniline

: 1449294-66-9
3-(2,4,6-trifluorophenyl)-2,4(1H,3H)-quinazolinedione

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / toluene / 2 h / Reflux

2: toluene / 2 h / Reflux

3: sodium hydroxide / ethanol / 0.5 h / 80 °C

With triethylamine; sodium hydroxide; In ethanol; toluene;
DOI:10.3987/COM-12-S(N)109