C₁₆H₁₈Cl₂FNO

Base Information

Chemical Name:C₁₆H₁₈Cl₂FNO
CAS No.:1384179-40-1
Molecular Formula:C₁₆H₁₈Cl₂FNO
Molecular Weight:330.229
Hs Code.:

C<sub>16</sub>H<sub>18</sub>Cl<sub>2</sub>FNO

Synonyms:

Suppliers and Price of C₁₆H₁₈Cl₂FNO

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₁₈Cl₂FNO

Chemical Property:

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Technology Process of C₁₆H₁₈Cl₂FNO

There total 3 articles about C₁₆H₁₈Cl₂FNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1384179-37-6
C₁₆H₁₉ClFNO₂

: 1384179-40-1
C₁₆H₁₈Cl₂FNO

Guidance literature:: With oxalyl dichloride; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1016/j.bmcl.2012.05.030

Reference yield:

: 146725-33-9
O 374

: 1384179-40-1
C₁₆H₁₈Cl₂FNO

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / acetonitrile / 12 h / 20 °C

2: hydrogenchloride; water / 12 h / Reflux

3: oxalyl dichloride / dichloromethane / 4 h / 20 °C

With hydrogenchloride; oxalyl dichloride; water; triethylamine; In dichloromethane; acetonitrile;
DOI:10.1016/j.bmcl.2012.05.030

Reference yield:

: 130342-80-2
2β-carbomethoxy-3β-(4-chlorophenyl)tropane

: 1384179-40-1
C₁₆H₁₈Cl₂FNO

Guidance literature:: Multi-step reaction with 4 steps

1.1: carbonochloridic acid 1-chloro-ethyl ester / 1,2-dichloro-ethane / 6 h / Reflux

1.2: 4 h / Reflux

2.1: triethylamine / acetonitrile / 12 h / 20 °C

3.1: hydrogenchloride; water / 12 h / Reflux

4.1: oxalyl dichloride / dichloromethane / 4 h / 20 °C

With hydrogenchloride; oxalyl dichloride; carbonochloridic acid 1-chloro-ethyl ester; water; triethylamine; In dichloromethane; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1016/j.bmcl.2012.05.030