C₂₄H₁₂N₂O₂S

Base Information

• Chemical Name: C₂₄H₁₂N₂O₂S
• CAS No.: 1933562-00-5
• Molecular Formula: C₂₄H₁₂N₂O₂S
• Molecular Weight: 392.437
• Mol file: 1933562-00-5.mol

Synonyms:

Chemical Property of C₂₄H₁₂N₂O₂S

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₁₂N₂O₂S

There total 3 articles about C₂₄H₁₂N₂O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

4,7-dibromobenzo[c][1,2,5]thiadiazole (15155-41-6) + 4-Ethynylbenzaldehyde (63697-96-1) → C24H12N2O2S (1933562-00-5)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In tetrahydrofuran; at 85 ℃; for 36h; Inert atmosphere;

DOI:10.1021/jacs.6b09787

Reference yield:

4-[(trimethylsilyl)ethynyl]bezaldehyde (77123-57-0) → C24H12N2O2S (1933562-00-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / methanol / 1 h / 20 °C

2: copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 36 h / 85 °C / Inert atmosphere

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; potassium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1021/jacs.6b09787

Reference yield:

4-bromo-benzaldehyde (1122-91-4) → C24H12N2O2S (1933562-00-5)

Guidance literature:

Multi-step reaction with 3 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

2: potassium hydroxide / methanol / 1 h / 20 °C

3: copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 36 h / 85 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; potassium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1021/jacs.6b09787

upstream raw materials:

4-[(trimethylsilyl)ethynyl]bezaldehyde

4,7-dibromobenzo[c][1,2,5]thiadiazole

4-Ethynylbenzaldehyde

4-bromo-benzaldehyde