(1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

Base Information

Chemical Name:(1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde
CAS No.:210559-97-0
Molecular Formula:C₂₂H₂₆O₂
Molecular Weight:322.447
Hs Code.:

Synonyms:

Suppliers and Price of (1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

There total 10 articles about (1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84884-01-5
1,2-dimethylcyclopent-2-ene carboxylic acid

: 210559-97-0
(1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) (+)-dehydroabiethylamine

2: Et₃N / tetrahydrofuran / 0.25 h / Ambient temperature

3: 4-dimethylaminopyridine / benzene / 4 h / Ambient temperature

4: Pd(OAc)2, (o-Tol)3P, Bu₃N / dimethylformamide / 12 h / 120 °C

5: H₂ / Pd/C / ethanol / 12 h / Ambient temperature

6: 92 percent / LiAlH₄ / tetrahydrofuran / 3 h / 0 °C

7: 86 percent / K₂CO₃ / acetonitrile / 8 h / Heating

8: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 1 h 2.) -78 deg C -> 0 deg C, 20 min

With dmap; palladium diacetate; lithium aluminium tetrahydride; oxalyl dichloride; tributyl-amine; leelamine; hydrogen; potassium carbonate; dimethyl sulfoxide; triethylamine; tris-(o-tolyl)phosphine; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetonitrile; benzene;
DOI:10.1246/cl.1998.485

Reference yield:

: 35928-80-4
6-iodo-3-methyl-phenol

: 210559-97-0
(1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: 4-dimethylaminopyridine / benzene / 4 h / Ambient temperature

2: Pd(OAc)2, (o-Tol)3P, Bu₃N / dimethylformamide / 12 h / 120 °C

3: H₂ / Pd/C / ethanol / 12 h / Ambient temperature

4: 92 percent / LiAlH₄ / tetrahydrofuran / 3 h / 0 °C

5: 86 percent / K₂CO₃ / acetonitrile / 8 h / Heating

6: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 1 h 2.) -78 deg C -> 0 deg C, 20 min

With dmap; palladium diacetate; lithium aluminium tetrahydride; oxalyl dichloride; tributyl-amine; hydrogen; potassium carbonate; dimethyl sulfoxide; triethylamine; tris-(o-tolyl)phosphine; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetonitrile; benzene;
DOI:10.1246/cl.1998.485

Reference yield:

: 210559-93-6
(S)-1,2-Dimethyl-cyclopent-2-enecarboxylic acid

: 210559-97-0
(1S,2S)-2-(2-Benzyloxy-4-methyl-phenyl)-1,2-dimethyl-cyclopentanecarbaldehyde

Guidance literature:: Multi-step reaction with 7 steps

1: Et₃N / tetrahydrofuran / 0.25 h / Ambient temperature

2: 4-dimethylaminopyridine / benzene / 4 h / Ambient temperature

3: Pd(OAc)2, (o-Tol)3P, Bu₃N / dimethylformamide / 12 h / 120 °C

4: H₂ / Pd/C / ethanol / 12 h / Ambient temperature

5: 92 percent / LiAlH₄ / tetrahydrofuran / 3 h / 0 °C

6: 86 percent / K₂CO₃ / acetonitrile / 8 h / Heating

7: 1.) DMSO, (COCl)2, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 1 h 2.) -78 deg C -> 0 deg C, 20 min

With dmap; palladium diacetate; lithium aluminium tetrahydride; oxalyl dichloride; tributyl-amine; hydrogen; potassium carbonate; dimethyl sulfoxide; triethylamine; tris-(o-tolyl)phosphine; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetonitrile; benzene;
DOI:10.1246/cl.1998.485