C₄₃H₆₉N₁₃O₉

Base Information

• Chemical Name: C₄₃H₆₉N₁₃O₉
• CAS No.: 1198076-80-0
• Molecular Formula: C₄₃H₆₉N₁₃O₉
• Molecular Weight: 912.103
• Mol file: 1198076-80-0.mol

Synonyms:

Chemical Property of C₄₃H₆₉N₁₃O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₆₉N₁₃O₉

There total 1 articles about C₄₃H₆₉N₁₃O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Leu-Wang resin + Fmoc-Pro-OH (71989-31-6) + Fmoc-Ile-OH (71989-23-6,251316-98-0) + Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) + Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine (187618-60-6) + Fmoc-L-propargyl-Gly-OH (198561-07-8) → C43H69N13O9 (1198076-80-0)

Guidance literature:

Fmoc-Leu-Wang resin; With piperidine; In N,N-dimethyl-formamide; Microwave irradiation; solid phase reaction;

Fmoc-Ile-OH; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; Microwave irradiation; solid phase reaction;

Fmoc-Pro-OH; Fmoc-Tyr(tBu)-OH; Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; Fmoc-L-propargyl-Gly-OH; Further stages;

DOI:10.1002/anie.200904137

Reference yield:

2-deoxy-2-fluoro-β-D-glucopyranosyl azide (1159265-95-8) + C43H69N13O9 (1198076-80-0) → C49H79FN16O13

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In ethanol; at 20 ℃; for 0.5h; aq. phosphate buffer;

DOI:10.1002/anie.200904137

Reference yield:

2-[18F]fluoro-2-deoxy-β-D-glucopyranosyl azide (1159266-05-3) + C43H69N13O9 (1198076-80-0) → C49H79(18)FN16O13 (1218933-02-8)

Guidance literature:

2-[¹⁸F]fluoro-2-deoxy-β-D-glucopyranosyl azide; With hydrogenchloride; In water;

C₄₃H₆₉N₁₃O₉; With copper(II) sulfate; sodium L-ascorbate; In ethanol; at 60 ℃; for 0.333333h; aq. phosphate buffer;

DOI:10.1002/anie.200904137

upstream raw materials:

Fmoc-Pro-OH

Fmoc-Ile-OH

Fmoc-Tyr(tBu)-OH

Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine

Downstream raw materials:

C₄₉H₇₉⁽¹⁸⁾FN₁₆O₁₃