C₅₈H₇₄N₈O₁₃S

Base Information

• Chemical Name: C₅₈H₇₄N₈O₁₃S
• CAS No.: 1273327-66-4
• Molecular Formula: C₅₈H₇₄N₈O₁₃S
• Molecular Weight: 1123.34
• Mol file: 1273327-66-4.mol

Synonyms:

Chemical Property of C₅₈H₇₄N₈O₁₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₈H₇₄N₈O₁₃S

There total 4 articles about C₅₈H₇₄N₈O₁₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C48H58N8O12S2 (1273327-69-7) → C58H74N8O13S (1273327-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; thiophenol / acetonitrile / 2 h / 20 °C

2: potassium hydrogencarbonate; HATU / N,N-dimethyl-formamide

With potassium carbonate; potassium hydrogencarbonate; thiophenol; HATU; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/cbic.201000572

Reference yield:

C20H21N3O7S (1273327-71-1) → C58H74N8O13S (1273327-66-4)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane

2: potassium carbonate; thiophenol / acetonitrile / 2 h / 20 °C

3: potassium hydrogencarbonate; HATU / N,N-dimethyl-formamide

With potassium carbonate; benzotriazol-1-ol; potassium hydrogencarbonate; thiophenol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; HATU; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/cbic.201000572

Reference yield:

H2N-Arg(Pbf)-Gly-OBn (1273327-72-2) → C58H74N8O13S (1273327-66-4)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane

2: potassium carbonate; thiophenol / acetonitrile / 2 h / 20 °C

3: potassium hydrogencarbonate; HATU / N,N-dimethyl-formamide

With potassium carbonate; benzotriazol-1-ol; potassium hydrogencarbonate; thiophenol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; HATU; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/cbic.201000572

upstream raw materials:

C₄₈H₅₈N₈O₁₂S₂

Z-D(tBu)-OH

C₂₀H₂₁N₃O₇S

H₂N-Arg(Pbf)-Gly-OBn

Downstream raw materials:

C₄₃H₆₀N₈O₁₀S

C₂₆H₃₆N₈O₇