4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid

Base Information

• Chemical Name: 4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid
• CAS No.: 1361411-70-2
• Molecular Formula: C₄₀H₅₁NO₇Si
• Molecular Weight: 685.933
• Mol file: 1361411-70-2.mol

Synonyms:

Chemical Property of 4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid

There total 1 articles about 4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C25H41NO5Si + N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → 4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid (1361411-70-2)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; at 0 - 20 ℃; for 19.5h;

DOI:10.1002/anie.201107222

Reference yield:

4-(4-{[(9H-fluoren-9-ylmethoxycarbonyl)-(3-trisopropylsilylprop-2-ynyl)amino]methyl}-3,5-dimethoxyphenoxy)butyric acid (1361411-70-2) → C40H51N2O6PolSi

Guidance literature:

With polyethylene glycol polyamide resin; N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; for 2h;

DOI:10.1002/anie.201107222

upstream raw materials:

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide