Technology Process of (+)-calystegine B4
There total 8 articles about (+)-calystegine B4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N,N,N',N'-tetramethylguanidine / N,N-dimethyl-formamide / 14 h / 20 °C / Inert atmosphere
2: water; acetic acid / tetrahydrofuran / 14 h / 40 °C / Inert atmosphere
3: Dess-Martin periodane / dichloromethane / 1 h / 20 °C / Inert atmosphere
4: N,N,N',N'-tetramethylguanidine / N,N-dimethyl-formamide / 48 h / 20 °C / Inert atmosphere
5: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 16 h / 20 °C / 37503.8 Torr / Inert atmosphere; Autoclave
6: hydrogenchloride; water / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere
7: Dowex SBR column / methanol
With
hydrogenchloride; palladium 10% on activated carbon; water; hydrogen; Dess-Martin periodane; acetic acid; N,N,N',N'-tetramethylguanidine;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c2ob25386k
- Guidance literature:
-
Multi-step reaction with 4 steps
1: N,N,N',N'-tetramethylguanidine / N,N-dimethyl-formamide / 48 h / 20 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 16 h / 20 °C / 37503.8 Torr / Inert atmosphere; Autoclave
3: hydrogenchloride; water / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere
4: Dowex SBR column / methanol
With
hydrogenchloride; palladium 10% on activated carbon; water; hydrogen; N,N,N',N'-tetramethylguanidine;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1039/c2ob25386k
