Technology Process of C43H51ClFN3O8
There total 12 articles about C43H51ClFN3O8 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1: sodium tetrahydroborate / ethanol / 0.5 h / 20 °C
2: pyridine / dichloromethane / 14 h / 20 °C
3: 1H-imidazole / dichloromethane / 20 °C
4: acetic acid / 15 h / 20 °C
5: triphenylphosphine; tetrachloromethane / 1,2-dichloro-ethane / 0.67 h / 130 °C / Microwave irradiation; Inert atmosphere
6: triethylamine; dmap / acetonitrile / 20 °C
7: ammonium hydroxide / acetonitrile / 2 h / 20 °C
8: silver nitrate; 2,4,6-trimethyl-pyridine / dichloromethane / 20 °C
9: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
10: pyridine / 20 °C
With
pyridine; 1H-imidazole; 2,4,6-trimethyl-pyridine; tetrachloromethane; dmap; ammonium hydroxide; sodium tetrahydroborate; tetrabutyl ammonium fluoride; silver nitrate; acetic acid; triethylamine; triphenylphosphine;
In
tetrahydrofuran; ethanol; dichloromethane; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1021/jm5017279
- Guidance literature:
-
Multi-step reaction with 3 steps
1: silver nitrate; 2,4,6-trimethyl-pyridine / dichloromethane / 20 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
3: pyridine / 20 °C
With
pyridine; 2,4,6-trimethyl-pyridine; tetrabutyl ammonium fluoride; silver nitrate;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jm5017279
- Guidance literature:
-
Multi-step reaction with 4 steps
1: ammonium hydroxide / acetonitrile / 2 h / 20 °C
2: silver nitrate; 2,4,6-trimethyl-pyridine / dichloromethane / 20 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
4: pyridine / 20 °C
With
pyridine; 2,4,6-trimethyl-pyridine; ammonium hydroxide; tetrabutyl ammonium fluoride; silver nitrate;
In
tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1021/jm5017279