Boc₂-Leu-ONp

Base Information

• Chemical Name: Boc₂-Leu-ONp
• CAS No.: 132090-29-0
• Molecular Formula: C₂₂H₃₂N₂O₈
• Molecular Weight: 452.505
• Mol file: 132090-29-0.mol

Synonyms:

Chemical Property of Boc₂-Leu-ONp

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc₂-Leu-ONp

There total 4 articles about Boc₂-Leu-ONp which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → Boc2-Leu-ONp (132090-29-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / DMAP / acetonitrile / Ambient temperature

2: H₂ / 5percent (w/w) Pd/C / methanol / 2 h

3: 51 percent / DCC / ethyl acetate / Ambient temperature

With dmap; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethyl acetate; acetonitrile;

Reference yield:

2-tert-butoxycarbonylamino-4-methyl-penatnoic acid benzyl ester (87746-56-3) → Boc2-Leu-ONp (132090-29-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / DMAP / acetonitrile / Ambient temperature

2: H₂ / 5percent (w/w) Pd/C / methanol / 2 h

3: 51 percent / DCC / ethyl acetate / Ambient temperature

With dmap; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethyl acetate; acetonitrile;

Reference yield:

C23H35NO6 (132090-16-5) → Boc2-Leu-ONp (132090-29-0)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 5percent (w/w) Pd/C / methanol / 2 h

2: 51 percent / DCC / ethyl acetate / Ambient temperature

With hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; ethyl acetate;

upstream raw materials:

di-tert-butyl dicarbonate

2-tert-butoxycarbonylamino-4-methyl-penatnoic acid benzyl ester

C₂₃H₃₅NO₆

caesium (2S)-2-[(tert-butoxycarbonyl)amino]-4-methylpentanoate