Technology Process of 3-(trans-2-hydroxycyclohexyl)-oxazolidin-2-one
There total 4 articles about 3-(trans-2-hydroxycyclohexyl)-oxazolidin-2-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate;
for 3h;
Ambient temperature;
DOI:10.1248/cpb.31.1646
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 61 percent / tetrahydrofuran / 0.5 h / Ambient temperature
2: 1.) sodium acetate, dinitrogen tetroxide / 1.) ethyl acetate, -5 deg C, 10 min; 2.) methanol, -5 deg C, 10 min
3: 95 percent / 10percent sodium bicarbonate / 3 h / Ambient temperature
With
sodium acetate; dinitrogen tetraoxide; sodium hydrogencarbonate;
In
tetrahydrofuran;
DOI:10.1248/cpb.31.1646
- Guidance literature:
-
Multi-step reaction with 4 steps
1: ethanol / 24 h / 150 °C
2: 61 percent / tetrahydrofuran / 0.5 h / Ambient temperature
3: 1.) sodium acetate, dinitrogen tetroxide / 1.) ethyl acetate, -5 deg C, 10 min; 2.) methanol, -5 deg C, 10 min
4: 95 percent / 10percent sodium bicarbonate / 3 h / Ambient temperature
With
sodium acetate; dinitrogen tetraoxide; sodium hydrogencarbonate;
In
tetrahydrofuran; ethanol;
DOI:10.1248/cpb.31.1646
