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C18H15F3N2O2

Base Information
  • Chemical Name:C18H15F3N2O2
  • CAS No.:1417826-27-7
  • Molecular Formula:C18H15F3N2O2
  • Molecular Weight:348.325
  • Hs Code.:
C<sub>18</sub>H<sub>15</sub>F<sub>3</sub>N<sub>2</sub>O<sub>2</sub>

Synonyms:

Suppliers and Price of C18H15F3N2O2
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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of C18H15F3N2O2
Chemical Property:
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Technology Process of C18H15F3N2O2

There total 2 articles about C18H15F3N2O2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; In 1,4-dioxane; at 90 - 110 ℃;
DOI:10.1016/j.bmcl.2012.09.059
Guidance literature:
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / ethanol / 120 °C
2: bis-triphenylphosphine-palladium(II) chloride; potassium acetate / 1,4-dioxane / 90 - 110 °C
With bis-triphenylphosphine-palladium(II) chloride; potassium acetate; sodium hydrogencarbonate; In 1,4-dioxane; ethanol; 2: |Heck Reaction;
DOI:10.1016/j.bmcl.2012.09.059
Guidance literature:
With bis(trimethylaluminum)–1,4-diazabicyclo[2.2.2]octane adduct; In tetrahydrofuran; at 40 ℃;
DOI:10.1016/j.bmcl.2012.09.059
upstream raw materials:

C11H12N2O2

3,5-dimethyl-pyridazine

ethyl Bromopyruvate

Downstream raw materials:

C20H20F3N3O2

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