(+)-(1S,2R)-1-morpholinoisonorborneol

Base Information

• Chemical Name: (+)-(1S,2R)-1-morpholinoisonorborneol
• CAS No.: 1187821-67-5
• Molecular Formula: C₁₃H₂₃NO₂
• Molecular Weight: 225.331
• Mol file: 1187821-67-5.mol

Synonyms:

Chemical Property of (+)-(1S,2R)-1-morpholinoisonorborneol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (+)-(1S,2R)-1-morpholinoisonorborneol

There total 2 articles about (+)-(1S,2R)-1-morpholinoisonorborneol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(1S)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]-heptan-2-one (1187821-64-2) → (+)-(1S,2R)-1-morpholinoisonorborneol (1187821-67-5)

Guidance literature:

(1S)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]-heptan-2-one; With sodium tetrahydroborate; cerium(III) chloride heptahydrate; In methanol; at -78 - 20 ℃;

With water; diastereoselective reaction;

DOI:10.1016/j.tetasy.2009.06.009

Reference yield: 88.0%

→ (+)-(1S,2R)-1-morpholinoisonorborneol (1187821-67-5)

Guidance literature:

upstream raw materials:

(1S)-7,7-dimethyl-1-morpholin-4-yl-bicyclo[2.2.1]-heptan-2-one