(1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol

Base Information

• Chemical Name: (1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol
• CAS No.: 90852-03-2
• Molecular Formula: C₆H₁₀I₂O₃
• Molecular Weight: 383.953
• Mol file: 90852-03-2.mol

Synonyms:

Chemical Property of (1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol

There total 10 articles about (1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1,2:4,5-cis-Dianhydrodesoxyinosit (62776-30-1,261919-41-9) → (1α,2α,3α,4β,6β)-4,6-Diiod-1,2,3-cyclohexantriol (90852-02-1,90899-11-9) + (1α,2α,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol (90852-03-2,90899-12-0)

Guidance literature:

With potassium iodide; In acetic acid; for 12h; Ambient temperature;

Reference yield: 78.0%

(1α,2α,3β,4α,5α)-1,2:4,5-dianhydro-1,2,3,4,5-cyclohexane-pentol (55990-89-1,261919-41-9) → (1α,2β,3α,4β,6β)-4,6-Diiod-1,2,3-cyclohexantriol (90852-02-1,90899-11-9) + (1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol (90852-03-2,90899-12-0)

Guidance literature:

With potassium iodide; In acetic acid; for 12h; Ambient temperature;

Reference yield:

2-bromo-7-oxabicyclo<4.1.0>hept-3-ene (72598-62-0) → (1α,2β,3β,4α,6β)-3,6-Diiod-1,2,4-cyclohexantriol (90852-03-2,90899-12-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 42 percent / acetone / 120 h / Ambient temperature

2: 89 percent / (CF₃CO)2O, 85percent H₂O₂, Na₂HPO₄ / CH₂Cl₂ / 12 h / 0 °C

3: ZnSO₄, NaN₃ / methanol / 14 h / Heating

4: 78 percent / KI / aq. acetic acid / 12 h / Ambient temperature

With disodium hydrogenphosphate; sodium azide; dihydrogen peroxide; zinc(II) sulfate; trifluoroacetic anhydride; potassium iodide; In methanol; dichloromethane; acetic acid; acetone;

upstream raw materials:

1,2:4,5-cis-Dianhydrodesoxyinosit

2-bromo-7-oxabicyclo<4.1.0>hept-3-ene

(1α,2α,3α,5α,7α)-2-Brom-4,8-dioxatricyclo<5.1.0.0^3,5>octan

(1α,2β,3α,5α,7α)-4,8-Dioxatricyclo<5.1.0.0^3,5>octan-2-ol-acetat