Gal6deoxy-1-P

Base Information

• Chemical Name: Gal6deoxy-1-P
• CAS No.: 81276-27-9
• Molecular Formula: C₆H₁₃O₈P
• Molecular Weight: 244.138
• Mol file: 81276-27-9.mol

Synonyms:

Chemical Property of Gal6deoxy-1-P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Gal6deoxy-1-P

There total 5 articles about Gal6deoxy-1-P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.4%

D-Fucose (73-34-7,87-96-7,488-79-9,551-63-3,609-01-8,643-17-4,643-18-5,4164-09-4,6014-42-2,6155-36-8,6189-71-5,6696-41-9,6736-43-2,13224-93-6,22611-09-2,28161-49-1,28161-50-4,28161-52-6,45864-36-6,63814-64-2,71116-59-1,71116-61-5,72598-05-1,87936-88-7,87936-89-8,97466-79-0,116908-82-8,120442-60-6,123484-22-0,133576-32-6) → Gal6deoxy-1-P (81276-27-9,28553-11-9)

Guidance literature:

With hydrogenchloride; Bifidobacterium infantis ATCC₁₅₆₉₇ galactokinase; ATP; 2-amino-2-hydroxymethyl-1,3-propanediol; magnesium chloride; In water; at 37 ℃; for 12h; pH=6.5; Enzymatic reaction;

DOI:10.1039/c5cc03746h

Reference yield:

→ β-L-Rhamnopyranosylphosphat (16562-58-6,16562-59-7,23880-96-8,24809-76-5,40591-48-8,40591-49-9,40591-52-4,62357-79-3,69980-07-0,81276-27-9,120522-69-2,28553-11-9)

Guidance literature:

Aus Pyranosylphosphat III, Pb(OAc)4, LiOH;

DOI:10.1007/BF00923209

Reference yield:

1,2,3,4-tetra-O-acetyl-D-fucopyranose (51921-33-6) → Gal6deoxy-1-P (81276-27-9,28553-11-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / 33percent HBr in glacial AcOH / CH₂Cl₂ / 0.5 h / 21 °C

2: Ag₂CO₃, H₂O

3: 1.) sym-collidine, 2.) sym-collidine, H₂O, 3.) Pb(OAc)4, 4.) aq. NaOH

With 2,4,6-trimethyl-pyridine; lead(IV) acetate; sodium hydroxide; water; hydrogen bromide; silver carbonate; In dichloromethane;

DOI:10.1006/bioo.1994.1012

upstream raw materials:

o-phenylene chlorophosphate

2,3,4-tri-O-acetyl-6-deoxy-α-D-galactopyranose

D-Fucose

2,3,4-tri-O-acetyl-D-fucopyranosyl bromide

Downstream raw materials:

UDP-6-deoxy-Gal

Refernces

• 1、 Li, Lei,Liu, Yonghui,Wang, Wenjun,Cheng, Jiansong,Zhao, Wei,Wang, Peng. "A highly efficient galactokinase from Bifidobacterium infantis with broad substrate specificity". experimental part. p. 35 - 39. Retrieved 2012/08/08.
• 2、 Faust,Theurer,Eger,Kreis. "Synthesis of uridine 5′(α-D-fucopyranosyl diphosphate) and (digitoxigenin-3β-yl)-β-D-fucopyranoside and enzymatic β-D-fucosylation of cardenolide aglycones in Digitalis lanata". . p. 140 - 149. Retrieved 2007/10/02.