7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester

Base Information

• Chemical Name: 7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester
• CAS No.: 92640-39-6
• Molecular Formula: C₂₉H₄₀O₈S
• Molecular Weight: 548.698
• Mol file: 92640-39-6.mol

Synonyms:

Chemical Property of 7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester

There total 1 articles about 7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 7-iodohept-5-ynoate (31776-12-2) + Lithium; (4R,5S)-4-[1-benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-4,5-dihydro-furan-2-olate → 7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester (92640-39-6)

Guidance literature:

at -45 ℃; for 2h; Yield given;

DOI:10.1246/cl.1984.707

Reference yield:

7-{(3R,4R,5S)-4-[1-Benzenesulfonyl-2-(2-pentyl-[1,3]dioxolan-2-yl)-ethyl]-5-methyl-2-oxo-tetrahydro-furan-3-yl}-hept-5-ynoic acid methyl ester (92640-39-6) → 7-[(3R,4R,5S)-4-(1-Benzenesulfonyl-3-oxo-octyl)-5-methyl-2-oxo-tetrahydro-furan-3-yl]-hept-5-ynoic acid methyl ester (92640-40-9)

Guidance literature:

With hydrogen fluoride; In acetonitrile; Ambient temperature;

DOI:10.1246/cl.1984.707

upstream raw materials:

methyl 7-iodohept-5-ynoate

Downstream raw materials:

7-[(3R,4R,5S)-4-(1-Benzenesulfonyl-3-oxo-octyl)-5-methyl-2-oxo-tetrahydro-furan-3-yl]-hept-5-ynoic acid methyl ester