C₂₁H₂₁N₅S

Base Information

• Chemical Name: C₂₁H₂₁N₅S
• CAS No.: 1204223-95-9
• Molecular Formula: C₂₁H₂₁N₅S
• Molecular Weight: 375.497
• Mol file: 1204223-95-9.mol

Synonyms:

Chemical Property of C₂₁H₂₁N₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₁N₅S

There total 3 articles about C₂₁H₂₁N₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H21N3O (1204222-62-7) + malononitrile (109-77-3) → C21H21N5S (1204223-95-9)

Guidance literature:

With morpholine; octasulfur; In tetrahydrofuran; ethanol; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2011.01.069

Reference yield:

C20H25N3O2 (1292304-19-8) → C21H21N5S (1204223-95-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water; acetone / 1 h / 60 °C

2: morpholine; octasulfur / tetrahydrofuran; ethanol / 1 h / 20 °C

With morpholine; hydrogenchloride; octasulfur; In tetrahydrofuran; ethanol; water; acetone; 2: Gewald reaction;

DOI:10.1016/j.bmcl.2011.01.069

Reference yield:

C11H17N3 (887594-74-3) → C21H21N5S (1204223-95-9)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 1 h / 0 °C

2: hydrogenchloride / water; acetone / 1 h / 60 °C

3: morpholine; octasulfur / tetrahydrofuran; ethanol / 1 h / 20 °C

With morpholine; hydrogenchloride; octasulfur; In tetrahydrofuran; methanol; ethanol; water; acetone; 3: Gewald reaction;

DOI:10.1016/j.bmcl.2011.01.069

upstream raw materials:

C₁₈H₂₁N₃O

malononitrile

C₁₁H₁₇N₃

C₂₀H₂₅N₃O₂

Downstream raw materials:

C₂₂H₂₄N₆O₂S

C₂₁H₂₃N₅OS