Technology Process of C16H20N2O4
There total 2 articles about C16H20N2O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diphenyl phosphoryl azide; triethylamine;
In
toluene;
at 20 ℃;
for 8.5h;
Reflux;
DOI:10.1016/j.bmcl.2012.12.078
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran; ethyl acetate / -78 °C
1.2: 20 °C
2.1: diphenyl phosphoryl azide; triethylamine / toluene / 8.5 h / 20 °C / Reflux
With
diphenyl phosphoryl azide; triethylamine; lithium hexamethyldisilazane;
In
tetrahydrofuran; ethyl acetate; toluene;
DOI:10.1016/j.bmcl.2012.12.078
- Guidance literature:
-
Multi-step reaction with 4 steps
1: palladium on activated charcoal; hydrogen / methanol / 4 h / 2585.81 Torr
2: triethylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / dichloromethane
3: lithium hydroxide monohydrate / water; 1,4-dioxane / 5 h / 70 °C
4: hydrogenchloride / 1,4-dioxane; ethanol / 100 °C / Microwave irradiation
With
hydrogenchloride; lithium hydroxide monohydrate; palladium on activated charcoal; hydrogen; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine;
In
1,4-dioxane; methanol; ethanol; dichloromethane; water;
DOI:10.1016/j.bmcl.2012.12.078
