(R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

Base Information

Chemical Name:(R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester
CAS No.:79701-40-9
Molecular Formula:C₄₀H₄₈N₄O₁₁
Molecular Weight:760.841
Hs Code.:

(R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

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Technology Process of (R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

There total 1 articles about (R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-4-((S)-2-Amino-3-phenyl-propionylamino)-4-carbamoyl-butyric acid methyl ester; compound with trifluoro-acetic acid

: 79734-49-9
1-O-benzyl-4,6-O-benzylidene-N-acetyl-α-muramic acid N-hydroxy-5-norbornene-2,3-dicarboxamide ester

: 79701-40-9
(R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

Guidance literature:: With triethylamine; In acetonitrile; Yield given; Ambient temperature;
DOI:10.1248/cpb.29.1644

Reference yield:

: 79701-40-9
(R)-4-{(S)-2-[2-((4aR,6S,7R,8R,8aS)-7-Acetylamino-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

: (R)-4-{(S)-2-[2-((2S,3R,4R,5S,6R)-3-Acetylamino-2,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yloxy)-propionylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyric acid methyl ester

Guidance literature:: With hydrogen; acetic acid; palladium; Yield given. Multistep reaction; 1.)30 min, 100 deg C 2.) acetic acid, room temp., 72 h;
DOI:10.1248/cpb.29.1644