Technology Process of methyl (2S,4S)-4-<(menthyloxycarbonyl)methyl>pyrrolidine-2-carboxylate
There total 6 articles about methyl (2S,4S)-4-<(menthyloxycarbonyl)methyl>pyrrolidine-2-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
for 2h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 98 percent / H2 / 10percent Pd-C / acetic acid / 12 h / 2068.6 Torr
2: 99 percent / NaHCO3 / 12 h / Ambient temperature
3: 72.5 percent / trifluoroacetic acid / CH2Cl2 / 6 h / Ambient temperature
4: 78 percent / DCC, DMAP / CH2Cl2; dimethylformamide / 13 h / Ambient temperature
5: 18 percent / H2 / 10percent Pd-C / methanol / 2 h / Ambient temperature
With
dmap; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; trifluoroacetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; acetic acid; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 34 percent / LDA / hexane; tetrahydrofuran / 2.5 h / -78 °C
2: 98 percent / H2 / 10percent Pd-C / acetic acid / 12 h / 2068.6 Torr
3: 99 percent / NaHCO3 / 12 h / Ambient temperature
4: 72.5 percent / trifluoroacetic acid / CH2Cl2 / 6 h / Ambient temperature
5: 78 percent / DCC, DMAP / CH2Cl2; dimethylformamide / 13 h / Ambient temperature
6: 18 percent / H2 / 10percent Pd-C / methanol / 2 h / Ambient temperature
With
dmap; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; trifluoroacetic acid; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; hexane; dichloromethane; acetic acid; N,N-dimethyl-formamide;
