C₁₇H₁₃BrClN₃O₂

Base Information

• Chemical Name: C₁₇H₁₃BrClN₃O₂
• CAS No.: 1277185-70-2
• Molecular Formula: C₁₇H₁₃BrClN₃O₂
• Molecular Weight: 406.666
• Mol file: 1277185-70-2.mol

Synonyms:

Chemical Property of C₁₇H₁₃BrClN₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₃BrClN₃O₂

There total 5 articles about C₁₇H₁₃BrClN₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

3-amino-5-bromo-1-benzofuran-2-carbohydrazide + para-chloroacetophenone (99-91-2) → C17H13BrClN3O2 (1277185-70-2)

Guidance literature:

In ethanol; for 4h; Acidic conditions; Reflux;

Reference yield:

5-bromosalicyclaldehyde (1761-61-1) → C17H13BrClN3O2 (1277185-70-2)

Guidance literature:

Multi-step reaction with 5 steps

1: hydroxylamine hydrochloride / N,N-dimethyl-formamide / 0.33 h / 155 - 160 °C

2: potassium carbonate / acetone / 8 h / Reflux

3: potassium carbonate / N,N-dimethyl-formamide / 7 h / Heating

4: hydrogenchloride; hydrazine hydrate / ethanol; water / 6 h / Reflux

5: ethanol / 4 h / Acidic conditions; Reflux

With hydrogenchloride; hydroxylamine hydrochloride; potassium carbonate; hydrazine hydrate; In ethanol; water; N,N-dimethyl-formamide; acetone;

Reference yield:

5-bromo-2-hydroxybenzonitrile (40530-18-5) → C17H13BrClN3O2 (1277185-70-2)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate / acetone / 8 h / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 7 h / Heating

3: hydrogenchloride; hydrazine hydrate / ethanol; water / 6 h / Reflux

4: ethanol / 4 h / Acidic conditions; Reflux

With hydrogenchloride; potassium carbonate; hydrazine hydrate; In ethanol; water; N,N-dimethyl-formamide; acetone;

upstream raw materials:

para-chloroacetophenone

5-bromosalicyclaldehyde

5-bromo-2-hydroxybenzonitrile

(4-bromo-2-cyanophenoxy)acetic acid ethyl ester

Downstream raw materials:

C₁₉H₁₁BrClN₃O₃