Technology Process of 2-(3-bromopyridin-4-yl)ethanol
There total 6 articles about 2-(3-bromopyridin-4-yl)ethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
methanol; sodium tetrahydroborate;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: bis(1,5-cyclooctadiene)nickel (0); triphenylphosphine / tetrahydrofuran / 1 h / 90 °C / Glovebox; Inert atmosphere; Schlenk technique
2: (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 1,10-Phenanthroline; norborn-2-ene / tetrahydrofuran / 12 h / 90 °C / Glovebox; Inert atmosphere; Schlenk technique
3: silver fluoride; N-Bromosuccinimide / 20 °C / Darkness
4: potassium hydride; tert.-butylhydroperoxide; tetrabutyl ammonium fluoride / tetrahydrofuran; decane / 3 h / 0 - 20 °C
With
tert.-butylhydroperoxide; norborn-2-ene; bis(1,5-cyclooctadiene)nickel (0); N-Bromosuccinimide; 1,10-Phenanthroline; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; tetrabutyl ammonium fluoride; silver fluoride; potassium hydride; triphenylphosphine;
In
tetrahydrofuran; decane;
DOI:10.1021/ol400977r
- Guidance literature:
-
With
tert.-butylhydroperoxide; tetrabutyl ammonium fluoride; potassium hydride;
In
tetrahydrofuran; decane;
at 0 - 20 ℃;
for 3h;
DOI:10.1021/ol400977r