C₁₁H₁₃IO₂

Base Information

• Chemical Name: C₁₁H₁₃IO₂
• CAS No.: 1612882-41-3
• Molecular Formula: C₁₁H₁₃IO₂
• Molecular Weight: 304.128
• Mol file: 1612882-41-3.mol

Synonyms:

Chemical Property of C₁₁H₁₃IO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₃IO₂

There total 6 articles about C₁₁H₁₃IO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (S)-(-)-p-(2-hydroxy-1-methylethyl)benzoate (145621-80-3) → C11H13IO2 (1612882-41-3)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In diethyl ether; acetonitrile; at 20 ℃; for 4.5h;

DOI:10.1002/adsc.201300250

Reference yield:

methyl 4-formylbenzoate (1571-08-0) → C11H13IO2 (1612882-41-3)

Guidance literature:

Multi-step reaction with 6 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 20 h / 0 °C

2: hydrogenchloride / tetrahydrofuran; water / Reflux

3: (5S)-(?)-2,2,3-trimethyl-5-benzyl-4-imidazolidinone monohydrochloride / water; acetonitrile / 24 h / 0 °C

4: sodium tetrahydroborate / methanol / 0.5 h / 0 °C

5: hydrogen / water; ethanol / 3 h / 760.05 Torr

6: iodine; 1H-imidazole; triphenylphosphine / acetonitrile; diethyl ether / 4.5 h / 20 °C

With 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; hydrogen; iodine; triphenylphosphine; lithium hexamethyldisilazane; (5S)-(?)-2,2,3-trimethyl-5-benzyl-4-imidazolidinone monohydrochloride; In tetrahydrofuran; methanol; diethyl ether; ethanol; water; acetonitrile;

DOI:10.1002/adsc.201300250

Reference yield:

cis-1-methoxy-2-(4-carbomethoxyphenyl)ethylene (119770-38-6) → C11H13IO2 (1612882-41-3)

Guidance literature:

Multi-step reaction with 5 steps

1: hydrogenchloride / tetrahydrofuran; water / Reflux

2: (5S)-(?)-2,2,3-trimethyl-5-benzyl-4-imidazolidinone monohydrochloride / water; acetonitrile / 24 h / 0 °C

3: sodium tetrahydroborate / methanol / 0.5 h / 0 °C

4: hydrogen / water; ethanol / 3 h / 760.05 Torr

5: iodine; 1H-imidazole; triphenylphosphine / acetonitrile; diethyl ether / 4.5 h / 20 °C

With 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; hydrogen; iodine; triphenylphosphine; (5S)-(?)-2,2,3-trimethyl-5-benzyl-4-imidazolidinone monohydrochloride; In tetrahydrofuran; methanol; diethyl ether; ethanol; water; acetonitrile;

DOI:10.1002/adsc.201300250

upstream raw materials:

methyl 4-formylbenzoate

cis-1-methoxy-2-(4-carbomethoxyphenyl)ethylene

4-carbomethoxyphenylacetaldehyde

C₁₇H₁₄O₃S₂