Technology Process of 2-
penam sulphone
There total 4 articles about 2-penam sulphone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1039/P19810000892
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 56 percent / 1M potassium t-butoxide / dimethylformamide; 2-methyl-propan-2-ol
2: 1.) methoxycarbonylmercury(II) acetate, 2.) hydrogen sulphide / 1.) methanol, dichloromethane, 3 h, room temperature, 2.) room temperature, 10 min
3: silica gel / tetrahydrofuran / 2 h
4: 2.4 equiv. m-chloroperbenzoic acid / CH2Cl2
With
methoxycarbonyl-mercury (II) acetate; hydrogen sulfide; potassium tert-butylate; silica gel; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1039/P19810000892
- Guidance literature:
-
Multi-step reaction with 2 steps
1: silica gel / tetrahydrofuran / 2 h
2: 2.4 equiv. m-chloroperbenzoic acid / CH2Cl2
With
silica gel; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane;
DOI:10.1039/P19810000892
