Technology Process of H-Lys(cHoc)-Ala-OBzl*Hydrochlorid
There total 5 articles about H-Lys(cHoc)-Ala-OBzl*Hydrochlorid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethyl acetate;
for 0.0833333h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) NaOH, CuSO4, NaHCO3, 2) 1 N HCl, H2S / 1) H2O, 2 h, 0 deg C, 20 h, RT
2: 86 percent / 4 N NaOH / dioxane; H2O / 6 h
3: 1) NMM, isobutylchloroformate, 2) NMM / 1) THF, -15 deg C, 2) THF, DMF, 2 h, -10 deg C, overnight, 4 deg C
4: 4 N HCl / ethyl acetate / 0.08 h / Ambient temperature
With
4-methyl-morpholine; hydrogenchloride; sodium hydroxide; hydrogen sulfide; sodium hydrogencarbonate; copper(II) sulfate; isobutyl chloroformate;
In
1,4-dioxane; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 86 percent / 4 N NaOH / dioxane; H2O / 6 h
2: 1) NMM, isobutylchloroformate, 2) NMM / 1) THF, -15 deg C, 2) THF, DMF, 2 h, -10 deg C, overnight, 4 deg C
3: 4 N HCl / ethyl acetate / 0.08 h / Ambient temperature
With
4-methyl-morpholine; hydrogenchloride; sodium hydroxide; isobutyl chloroformate;
In
1,4-dioxane; water; ethyl acetate;