Technology Process of C64H78N14O12
There total 14 articles about C64H78N14O12 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 93 percent / CH2Cl2 / 0.08 h / 0 °C
2: 75 percent / 40percent HBr/HOAc / 0.25 h / 23 °C
3: 1. LiOH 2. dicyclohexylcarbodimide, N-hydroxybenzotriazole / 1. THF, H2O 2. DMF
With
lithium hydroxide; hydrogen bromide; benzotriazol-1-ol; acetic acid; dicyclohexyl-carbodiimide;
In
dichloromethane;
DOI:10.1021/jo00302a033
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 53 percent / Dowtherm A / 0.25 h / Heating
2: 1.96 g / SnCl2*2H2O / aq. HCl / 0.17 h / Heating
3: 1. NaAlCl4 2. H2SO4 / 1. 160 deg C, 1 h 2. H2O
4: 76 percent / triethylamine / dimethylsulfoxide / 1 h
5: trifluoroacetic acid / CH2Cl2 / 0.17 h / 0 °C
6: triethylamine / dimethylformamide / 4 h
7: 1. trifluoroacetic acid 2. triethylamine / 2. DMF
8: 1. LiOH 2. dicyclohexylcarbodimide, N-hydroxybenzotriazole / 1. THF, H2O 2. DMF
With
lithium hydroxide; diphenyl ether-biphenyl eutectic; sodium tetrachloroaluminate; sulfuric acid; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; tin(ll) chloride;
In
hydrogenchloride; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/jo00302a033
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1. NaAlCl4 2. H2SO4 / 1. 160 deg C, 1 h 2. H2O
2: 76 percent / triethylamine / dimethylsulfoxide / 1 h
3: trifluoroacetic acid / CH2Cl2 / 0.17 h / 0 °C
4: triethylamine / dimethylformamide / 4 h
5: 1. trifluoroacetic acid 2. triethylamine / 2. DMF
6: 1. LiOH 2. dicyclohexylcarbodimide, N-hydroxybenzotriazole / 1. THF, H2O 2. DMF
With
lithium hydroxide; sodium tetrachloroaluminate; sulfuric acid; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid;
In
dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1021/jo00302a033