8-acetyl-1-methyloctahydro-4(1H)-azulenone

Base Information

• Chemical Name: 8-acetyl-1-methyloctahydro-4(1H)-azulenone
• CAS No.: 132842-97-8
• Molecular Formula: C₁₃H₂₀O₂
• Molecular Weight: 208.301
• Mol file: 132842-97-8.mol

Synonyms:

Chemical Property of 8-acetyl-1-methyloctahydro-4(1H)-azulenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 8-acetyl-1-methyloctahydro-4(1H)-azulenone

There total 1 articles about 8-acetyl-1-methyloctahydro-4(1H)-azulenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-isoapoaromadendrone (132842-92-3) → (1R,3aR,8R,8aR)-8-Hydroxy-1-methyl-octahydro-azulen-4-one (132842-96-7) + (1R,3aR,8R,8aS)-8-Acetyl-1-methyl-octahydro-azulen-4-one (132842-97-8) + Acetic acid (3R,3aR,4R,8aR)-3-methyl-8-oxo-decahydro-azulen-4-yl ester (132842-95-6)

Guidance literature:

With dmap; oxygen; acetic anhydride; ozone; triethylamine; Yield given. Multistep reaction. Yields of byproduct given; 1) CCl₄/MeOH, -30 deg C, 45 min., 2) a) -30 deg C, 10 min., b) 0 deg C, 1 h;

DOI:10.1016/S0040-4020(01)87904-7

upstream raw materials:

(-)-isoapoaromadendrone