3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Base Information

Chemical Name:3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid
CAS No.:1275617-44-1
Molecular Formula:C₂₇H₄₂N₄O₈SSi
Molecular Weight:610.804
Hs Code.:

3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Synonyms:

Suppliers and Price of 3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

There total 3 articles about 3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₀H₄₆N₄O₈SSi

: 1275617-44-1
3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Guidance literature:: With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm1014023

Reference yield:

: C₄₉H₆₀N₄O₈SSi

: 1275617-44-1
3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / methanol / 2 h / 20 °C / Inert atmosphere

2: morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; toluene-4-sulfonic acid; In tetrahydrofuran; methanol;
DOI:10.1021/jm1014023

Reference yield:

: 173152-60-8
allyl 2-{(R)-2-amino-2-[3-methyl-1,2,4-oxadiazol-5-yl]-ethylsulfanylmethyl}-3-[dimethyl(thexyl)silyloxy]-5-methoxy-6-methylbenzoate

: 1275617-44-1
3-[dimethyl(thexyl)silyloxy]-2-[(R)-2-[2-(2-hydroxyacetylamino)acetylamino]-2-(3-methyl-1,2,4-oxadiazol-5-yl)ethylsulfanylmethyl]-5-methoxy-6-methylbenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1,2-dichloro-ethane / acetonitrile / 5 h / 0 °C / Inert atmosphere

2: toluene-4-sulfonic acid / methanol / 2 h / 20 °C / Inert atmosphere

3: morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; toluene-4-sulfonic acid; 1,2-dichloro-ethane; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1021/jm1014023