1-Hydroxy-2-naphthyl-2-methoxystyrylketon

Base Information

• Chemical Name: 1-Hydroxy-2-naphthyl-2-methoxystyrylketon
• CAS No.: 28753-47-1
• Molecular Formula: C₂₀H₁₆O₃
• Molecular Weight: 304.345
• Mol file: 28753-47-1.mol

Synonyms:

Chemical Property of 1-Hydroxy-2-naphthyl-2-methoxystyrylketon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Hydroxy-2-naphthyl-2-methoxystyrylketon

There total 2 articles about 1-Hydroxy-2-naphthyl-2-methoxystyrylketon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-hydroxy-1-naphthyl)ethan-1-one (574-19-6) + ortho-anisaldehyde (135-02-4) → 1-Hydroxy-2-naphthyl-2-methoxystyrylketon (28753-47-1)

Guidance literature:

With potassium hydroxide; In ethanol;

DOI:10.1016/j.molcatb.2015.04.007

Reference yield:

→ 1-(2-Hydroxy-1-naphthyl)-3-(2-methoxyphenyl)-prop-2-en-1-on (28753-47-1)

Guidance literature:

2-Methoxybenzaldehyd in A., 1-Acetyl-2-naphthol in A., NaOH in W.;

Reference yield:

1-Hydroxy-2-naphthyl-2-methoxystyrylketon (28753-47-1) → 3-(2-methoxyphenyl)-1H-naphtho[2,1-b]pyran-1-one

Guidance literature:

With iodine; In dimethyl sulfoxide; for 3h; Reflux;

DOI:10.1002/mrc.3790

upstream raw materials:

1-(2-hydroxy-1-naphthyl)ethan-1-one

ortho-anisaldehyde

Downstream raw materials:

3-(2-hydroxynaphthalen-1-yl)-5-(2-methoxyphenyl)-N-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide

3-(2-hydroxynaphthalen-1-yl)-5-(2-methoxyphenyl)-N-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

3-(2-hydroxynaphthalen-1-yl)-N,5-bis(2-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

3-(2-hydroxynaphthalen-1-yl)-5-(2-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Refernces