C₂₁H₂₇NO₅

Base Information

• Chemical Name: C₂₁H₂₇NO₅
• CAS No.: 1356687-12-1
• Molecular Formula: C₂₁H₂₇NO₅
• Molecular Weight: 373.449
• Mol file: 1356687-12-1.mol

Synonyms:

Chemical Property of C₂₁H₂₇NO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₂₇NO₅

There total 2 articles about C₂₁H₂₇NO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methyl-2H-pyran-2-one (31678-73-6) → C21H27NO5 (1356687-12-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: diethyl ether / -10 °C / Irradiation; Inert atmosphere

2.1: sodium hydride / tetrahydrofuran; mineral oil / 20 °C / Inert atmosphere

2.2: 1.5 h / 40 °C / Inert atmosphere

3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

With sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; diethyl ether; dichloromethane; mineral oil;

DOI:10.1002/anie.201106321

Reference yield:

4-methyl-2-oxabicyclo[2.2.0]hex-5-en-3-one → C21H27NO5 (1356687-12-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 20 °C / Inert atmosphere

1.2: 1.5 h / 40 °C / Inert atmosphere

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere

With sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1002/anie.201106321

upstream raw materials:

3-methyl-2H-pyran-2-one