Technology Process of 4-(3-bromophenyl)-6-phenyl-dibenzothiophene
There total 1 articles about 4-(3-bromophenyl)-6-phenyl-dibenzothiophene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine;
In
ethanol; water; toluene;
at 80 ℃;
for 4h;
Inert atmosphere;
- Guidance literature:
-
4-(3-bromophenyl)-6-phenyldibenzothiophene;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 2h;
Inert atmosphere;
Trimethyl borate;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
for 16h;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; hexane; water;
at 20 ℃;
for 2.5h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere
1.2: 16 h / -78 - 20 °C / Inert atmosphere
1.3: 2.5 h / 20 °C
2.1: palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine / toluene; ethanol; water / 6 h / 80 °C / Inert atmosphere
With
n-butyllithium; palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine;
In
tetrahydrofuran; ethanol; hexane; water; toluene;
2.1: |Suzuki-Miyaura Coupling;
