Technology Process of C18H19N3O5
There total 3 articles about C18H19N3O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C15H21N3O5;
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 18h;
Inert atmosphere;
benzyl chloroformate;
With
sodium carbonate;
In
1,4-dioxane; water;
at 20 ℃;
for 18h;
Inert atmosphere;
DOI:10.1021/ml300277t
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere; Large scale
1.2: -78 - 20 °C / Inert atmosphere; Large scale
2.1: acetic acid / 18 h / 50 °C / Inert atmosphere
3.1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C / Inert atmosphere
3.2: 18 h / 20 °C / Inert atmosphere
With
acetic acid; trifluoroacetic acid; lithium hexamethyldisilazane;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/ml300277t
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid / 18 h / 50 °C / Inert atmosphere
2.1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C / Inert atmosphere
2.2: 18 h / 20 °C / Inert atmosphere
With
acetic acid; trifluoroacetic acid;
In
dichloromethane;
DOI:10.1021/ml300277t