p-(trifluorovinyl)acetophenone ethylene ketal

Base Information

• Chemical Name: p-(trifluorovinyl)acetophenone ethylene ketal
• CAS No.: 122977-29-1
• Molecular Formula: C₁₂H₁₁F₃O₂
• Molecular Weight: 244.213
• Mol file: 122977-29-1.mol

Synonyms:

Chemical Property of p-(trifluorovinyl)acetophenone ethylene ketal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of p-(trifluorovinyl)acetophenone ethylene ketal

There total 1 articles about p-(trifluorovinyl)acetophenone ethylene ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + 2-(4-bromophenyl)-2-methyl-1,3-dioxolane (4360-68-3) → p-(trifluorovinyl)acetophenone ethylene ketal (122977-29-1) + C22H22F2O4

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; Yield given. Multistep reaction; 1) ether, hexane, 20 deg C, 4h, 2) -100 deg C, 1h;

DOI:10.1021/jo01302a030

Reference yield:

p-(trifluorovinyl)acetophenone ethylene ketal (122977-29-1) → 1-(4-(1,2,2-trifluorovinyl)phenyl)ethanone (73558-52-8)

Guidance literature:

With methanol; sulfuric acid; water; at 50 ℃; for 1h; Yield given;

DOI:10.1021/jo01302a030

upstream raw materials:

polytetrafluoroethylene

2-(4-bromophenyl)-2-methyl-1,3-dioxolane

Downstream raw materials:

1-(4-(1,2,2-trifluorovinyl)phenyl)ethanone

Refernces