(2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid

Base Information

Chemical Name:(2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid
CAS No.:53616-19-6
Molecular Formula:C11H11 N O3
Molecular Weight:205.213
Hs Code.:
NSC Number:52606
DSSTox Substance ID:DTXSID801219145
Nikkaji Number:J1.034.824B
Mol file:53616-19-6.mol

Synonyms:53616-19-6;(2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid;4-Oxo-4-(o-tolylamino)but-2-enoic acid;3-o-Tolylcarbamoyl-acrylic acid;o-methylmaleanilic acid;(Z)-4-(2-methylanilino)-4-oxobut-2-enoic acid;SCHEMBL9360564;N-(2-Methylphenyl)maleamic acid;DTXSID801219145;N-(2-Methylphenyl)maleamidic acid;NSC52606;BBL018594;MFCD00452548;NSC-52606;STK720158;AKOS000296014;VS-06707;CS-0363228;(Z)-4-oxo-4-(o-tolylamino)but-2-enoic acid;(2Z)-4-[(2-Methylphenyl)amino]-4-oxo-2-butenoic acid;(2Z)-3-[(2-METHYLPHENYL)CARBAMOYL]PROP-2-ENOIC ACID

Suppliers and Price of (2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid

Chemical Property:

Vapor Pressure:1.89E-08mmHg at 25°C
Boiling Point:438.1°C at 760 mmHg
Flash Point:218.8°C
Density:1.282g/cm³
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.07389321
Heavy Atom Count:15
Complexity:273

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=O)C=CC(=O)O
Isomeric SMILES:CC1=CC=CC=C1NC(=O)/C=C\C(=O)O

Technology Process of (2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid

There total 2 articles about (2Z)-4-[(2-methylphenyl)amino]-4-oxobut-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 108-31-6
maleic anhydride

: 95-53-4
o-toluidine

: 53616-19-6
(2-methylphenyl)maleamic acid

Guidance literature:: In diethyl ether; at 20 ℃;

Reference yield:

: 53616-19-6
(2-methylphenyl)maleamic acid

Guidance literature:: o-Toluidin u. Maleinsaeureanhydrid in Ae. oder Bzl.;

Reference yield: 96.0%

: 53616-19-6
(2-methylphenyl)maleamic acid

: diethyl 4,4'-(1E,1'E)-(4-oxopiperidine-3,5-diylidene)bis(methan-1-yl-1-ylidene)dibenzoate acetic acid salt

: (2Z)-4-(3E,5E)-(3,5-bis-(4-carboethoxybenzylidene)-4-oxopiperidin-1-yl)-4-oxobut-2-enoic acid (2-methylphenyl)amide

Guidance literature:: (2-methylphenyl)maleamic acid; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at 20 ℃; for 24h;

diethyl 4,4'-(1E,1'E)-(4-oxopiperidine-3,5-diylidene)bis(methan-1-yl-1-ylidene)dibenzoate acetic acid salt; With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 24h;
DOI:10.1016/j.bmc.2015.08.023