Chemical Property of Acid-PEG3-t-butyl ester
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Chemical Property:
- Boiling Point:423.2±35.0 °C(Predicted)
- PKA:4.28±0.10(Predicted)
- Density:1.106±0.06 g/cm3(Predicted)
- Solubility.:Soluble in Water, DMSO, DCM, DMF
- Purity/Quality:
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98%,99%, *data from raw suppliers
Acid-PEG3-t-butylester 95% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
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Description
Acid-PEG3-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.