14-oxopodocarpa-8⁽⁹⁾-ene

Base Information

• Chemical Name: 14-oxopodocarpa-8⁽⁹⁾-ene
• CAS No.: 135854-66-9
• Molecular Formula: C₁₇H₂₆O
• Molecular Weight: 246.393
• Mol file: 135854-66-9.mol

Synonyms:

Chemical Property of 14-oxopodocarpa-8⁽⁹⁾-ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 14-oxopodocarpa-8⁽⁹⁾-ene

There total 1 articles about 14-oxopodocarpa-8⁽⁹⁾-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-14-methoxypodocarpa-8,11,13-triene (5720-79-6,38011-84-6,105999-32-4,109555-92-2) → (4aR,4bS,8aR,10aS)-4b,8,8-Trimethyl-4a,4b,5,6,7,8,8a,9,10,10a-decahydro-4H-phenanthren-1-one (57684-15-8,98574-06-2,135968-56-8) + 14-oxopodocarpa-8(9)-ene (135854-66-9)

Guidance literature:

With ethanol; ammonia; lithium; tert-butyl alcohol; Multistep reaction; 1.) THF, 2.) acid hydrolysis;

Reference yield:

14-oxopodocarpa-8(9)-ene (135854-66-9) → (+/-)-veadeiroic acid (69903-86-2,111958-09-9)

Guidance literature:

Multi-step reaction with 5 steps

1: BF₃-Et₂O, diisopropylethylamine

2: 80 percent / tetrahydrofuran / sonication

3: H₃O⁺ / hydrolysis

4: MnO₂ / benzene / Heating

5: Ag₂O

With manganese(IV) oxide; boron trifluoride diethyl etherate; oxonium; N-ethyl-N,N-diisopropylamine; silver(l) oxide; In tetrahydrofuran; benzene;

Reference yield:

14-oxopodocarpa-8(9)-ene (135854-66-9) → (+/-)-veadeirol (69940-49-4,111958-10-2)

Guidance literature:

Multi-step reaction with 6 steps

1: BF₃-Et₂O, diisopropylethylamine

2: 80 percent / tetrahydrofuran / sonication

3: H₃O⁺ / hydrolysis

4: MnO₂ / benzene / Heating

5: Ag₂O

6: LiAlH₄

With manganese(IV) oxide; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; oxonium; N-ethyl-N,N-diisopropylamine; silver(l) oxide; In tetrahydrofuran; benzene;

upstream raw materials:

(+/-)-14-methoxypodocarpa-8,11,13-triene

Downstream raw materials:

(+/-)-veadeirol

(+/-)-veadeiroic acid