Mal-PEG2-amine

Base Information

Chemical Name:Mal-PEG2-amine
CAS No.:660843-22-1
Molecular Formula:C₁₀H₁₆N₂O₄
Molecular Weight:228.248
Hs Code.:
Mol file:660843-22-1.mol

Synonyms:

Suppliers and Price of Mal-PEG2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
Mal-PEG2-amineTFAsalt 98%
1 G
$ 1100.00

BroadPharm
Mal-PEG2-amineTFAsalt 98%
500 MG
$ 680.00

BroadPharm
Mal-PEG2-amineTFAsalt 98%
250 MG
$ 480.00

BroadPharm
Mal-PEG2-amineTFAsalt 98%
100 MG
$ 320.00

Total 12 raw suppliers

Chemical Property of Mal-PEG2-amine

Chemical Property:

Boiling Point:379.9±27.0 °C(Predicted)
PKA:8.74±0.10(Predicted)
Density:1.226±0.06 g/cm3(Predicted)
Solubility.:Soluble in Water, DMSO, DCM, DMF

Purity/Quality:

97% ^*data from raw suppliers

Mal-PEG2-amineTFAsalt 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Mal-PEG2-amine TFA salt is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Technology Process of Mal-PEG2-amine

There total 2 articles about Mal-PEG2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 660843-21-0
tert-butyl N-(2-{2-[2-(2,5-dioxo-2,5-dihydro-iH-pyrrol-1-yl)ethoxy]ethoxy}ethyl)carbamate

: 660843-22-1
1-{2- [2-(2-aminoethoxy)ethoxy]ethyl}-2,5-dihydro-1H-pyrrole-2,5-dione

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 1.33333h;
DOI:10.1002/chem.201800028

Reference yield:

: 153086-78-3
tert-butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate

: 660843-22-1
1-{2- [2-(2-aminoethoxy)ethoxy]ethyl}-2,5-dihydro-1H-pyrrole-2,5-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / 0.25 h / 0 °C

1.2: 0 - 20 °C

2.1: trifluoroacetic acid / dichloromethane / 1.33 h / 0 - 20 °C

With sodium hydrogencarbonate; trifluoroacetic acid; In dichloromethane;
DOI:10.1002/chem.201800028