Technology Process of (E)-1,4-di-(1-naphthyl)butenyne
There total 9 articles about (E)-1,4-di-(1-naphthyl)butenyne which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
[1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; potassium tert-butylate;
In
toluene;
at 60 ℃;
for 3h;
Reagent/catalyst;
Solvent;
stereoselective reaction;
Inert atmosphere;
Schlenk technique;
DOI:10.1016/j.jorganchem.2017.12.041
- Guidance literature:
-
With
[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; acetic acid;
In
tetrahydrofuran; methanol; water;
at 20 ℃;
for 24h;
optical yield given as %de;
stereoselective reaction;
Inert atmosphere;
DOI:10.1002/adsc.201000347
- Guidance literature:
-
Multi-step reaction with 3 steps
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 60 °C / Inert atmosphere
2: methanol; potassium carbonate / dichloromethane / 2 h / 20 °C
3: bis(N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)palladium(0); tris(2,6-dimethoxyphenyl)phosphine / toluene / 24 h / 60 °C / Inert atmosphere
With
methanol; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; bis(N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)palladium(0); potassium carbonate; tris(2,6-dimethoxyphenyl)phosphine; triethylamine;
In
tetrahydrofuran; dichloromethane; toluene;
1: Sonogashira coupling;
DOI:10.1021/ol3010936
