12-Chloro-10,11-dihydro-5h-5,10-methanodibenzo[a,d][7]annulen-11-ol

Base Information

• Chemical Name: 12-Chloro-10,11-dihydro-5h-5,10-methanodibenzo[a,d][7]annulen-11-ol
• CAS No.: 65556-45-8
• Molecular Formula: C₁₆H₁₃ClO
• Molecular Weight: 256.732
• NSC Number: 123013
• DSSTox Substance ID: DTXSID30984142
• Mol file: 65556-45-8.mol

Synonyms:65556-45-8;NSC123013;12-chloro-10,11-dihydro-5h-5,10-methanodibenzo[a,d][7]annulen-11-ol;DTXSID30984142;NSC-123013

Chemical Property of 12-Chloro-10,11-dihydro-5h-5,10-methanodibenzo[a,d][7]annulen-11-ol

Chemical Property:

• Vapor Pressure: 9.92E-08mmHg at 25°C
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 256.0654927
• Heavy Atom Count: 18
• Complexity: 331

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C3C(C(C2=C1)C(C4=CC=CC=C34)O)Cl

Technology Process of 12-Chloro-10,11-dihydro-5h-5,10-methanodibenzo[a,d][7]annulen-11-ol

There total 5 articles about 12-Chloro-10,11-dihydro-5h-5,10-methanodibenzo[a,d][7]annulen-11-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

anti-8-Chlordibenzobicyclo<3.2.1>octadien-exo-2-ol-acetat → C16H13ClO (65556-45-8)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja01091a017

Reference yield:

trans-7,8-dichloro-2,3:5,6-dibenzobicyclo<2.2.2>octa-2,5-diene (6476-15-9) → C16H13ClO (65556-45-8)

Guidance literature:

Multi-step reaction with 2 steps

1: AgOAc

2: LiAlH₄

With lithium aluminium tetrahydride; silver(I) acetate;

DOI:10.1021/ja01091a017

Reference yield:

exo-4-syn-8-dichloro-2,3:6,7-dibenzobicyclo<3.2.1>octa-2,6-diene (2197-98-0) → 8syn-Chlor-2endo-hydroxy-dibenzobicyclo<3.2.1>octadien (65556-45-8)

Guidance literature:

Multistep reaction; (i) tBuCO₂H, tBuCO₂Ag, (ii) LiAlH₄;

DOI:10.1021/ja01069a030

upstream raw materials:

trans-7,8-dichloro-2,3:5,6-dibenzobicyclo<2.2.2>octa-2,5-diene

9,10-dihydro-9,10-etheno-anthracene

exo-4-syn-8-dichloro-2,3:6,7-dibenzobicyclo<3.2.1>octa-2,6-diene