Globomycin

Base Information

• Chemical Name: Globomycin
• CAS No.: 64441-34-5
• Deprecated CAS: 64441-34-5
• Molecular Formula: C₃₂H₅₇N₅O₉
• Molecular Weight: 655.833
• DSSTox Substance ID: DTXSID10983012
• Wikidata: Q27106746
• Metabolomics Workbench ID: 99212
• Mol file: 64441-34-5.mol

Synonyms:globomycin;Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxononyl)-N-methylleucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone;SF-1902;SF-1902 A2;SF-1902 A3;SF-1902 A4a;SF-1902 A4b;SF-1902 A5

Chemical Property of Globomycin

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 11
• Exact Mass: 655.41562841
• Heavy Atom Count: 46
• Complexity: 1040

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCC1C(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)O1)C(C)O)CO)C(C)CC)CC(C)C)C)C

Technology Process of Globomycin

There total 58 articles about Globomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

25-epi-24-O-benzyl-globomycin (694528-07-9) → 25-epi-globomycin (64441-34-5)

Guidance literature:

With hydrogen; palladium dihydroxide; In methanol; at 20 ℃; for 11h;

DOI:10.1016/j.bmc.2003.10.055

Reference yield: 96.0%

O-benzyl globomycin (308279-80-3) → globomycin (64441-34-5)

Guidance literature:

With hydrogen; palladium dihydroxide;

DOI:10.1016/S0040-4020(03)00110-8

Reference yield: 95.0%

4-epi-24-O-benzyl-globomycin (694528-18-2) → 4-epi-globomycin (64441-34-5)

Guidance literature:

With hydrogen; palladium dihydroxide; In methanol; at 20 ℃; for 11h;

DOI:10.1016/j.bmc.2003.10.055

upstream raw materials:

O-benzyl globomycin

[2-tert-butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-butyrylamino]-acetic acid benzyl ester

(S)-3-Benzyloxy-2-((2S,3R)-2-{(S)-2-[((2R,3R)-3-hydroxy-2-methyl-nonanoyl)-methyl-amino]-4-methyl-pentanoylamino}-3-methyl-pentanoylamino)-propionic acid allyl ester

(S)-3-Benzyloxy-2-{(2S,3R)-2-[(S)-2-({(2R,3R)-3-[2-((2S,3S)-2-tert-butoxycarbonylamino-3-hydroxy-butyrylamino)-acetoxy]-2-methyl-nonanoyl}-methyl-amino)-4-methyl-pentanoylamino]-3-methyl-pentanoylamino}-propionic acid