2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol

Base Information

Chemical Name:2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol
CAS No.:60286-30-8
Molecular Formula:C₂₁H₃₆N₈O₅
Molecular Weight:480.567
Hs Code.:2933599550
UNII:9HOE8AZZ8G
DSSTox Substance ID:DTXSID60209037
Wikidata:Q27272572
Mol file:60286-30-8.mol

Synonyms:60286-30-8;Dipyridamole impurity F;UNII-9HOE8AZZ8G;9HOE8AZZ8G;(DipyridaMole IMpurity);2-[[2,6-bis[bis(2-hydroxyethyl)amino]-4-piperidin-1-ylpyrimido[5,4-d]pyrimidin-8-yl]amino]ethanol;2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol;2,2',2'',2'''-[[4-[(2-Hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol;(Dipyridamole Impurity)"";SCHEMBL17896293;DTXSID60209037;2,6-Di[di(2-hydroxyethyl)amino]-4-(2-hydroxyethyl)amino-8-(piperidin-1-yl)-pyrimido[5,4-d]pyrimidine;DIPYRIDAMOLE IMPURITY F [EP IMPURITY];A899807;Q27272572;2,2',2'',2'''-[[4-[(2-Hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol(Dipyridamole Impurity);ETHANOL, 2,2',2'',2'''-((4-((2-HYDROXYETHYL)AMINO)-8-(1-PIPERIDINYL)PYRIMIDO(5,4-D)PYRIMIDINE-2,6-DIYL)DINITRILO)TETRAKIS

Suppliers and Price of 2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2'',2'''',2''''''-[[4-[(2-Hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol(DipyridamoleImpurity)
10mg
$ 165.00

Medical Isotopes, Inc.
2,2??,2????,2??????-[[4-[(2-Hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol(DipyridamoleImpurity)
10 mg
$ 650.00

Total 14 raw suppliers

Chemical Property of 2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol

Chemical Property:

Melting Point:152-154 °C
Boiling Point:834.3±75.0 °C(Predicted)
PKA:13.84±0.10(Predicted)
Density:1.437±0.06 g/cm3(Predicted)
XLogP3:-1
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:14
Exact Mass:480.28086628
Heavy Atom Count:34
Complexity:549

Purity/Quality:

97% ^*data from raw suppliers

2,2'',2'''',2''''''-[[4-[(2-Hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol(DipyridamoleImpurity) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3NCCO)N(CCO)CCO)N(CCO)CCO
Uses 2,2',2'',2'''-[[4-[(2-hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol, is an impurity of Dipyridamole (D492625), which is a selective inhibitor of phosphodiesterase V (PDE 5), a potent coronary vasodilator drug, an adenosine transport inhibitor, and inhibitor of platelet aggregation. 2,2'',2'''',2''''''-[[4-[(2-hydroxyethyl)amino]-8-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol (Dipyridamole EP Impurity F), is an impurity of Dipyridamole (D492625), which is a selective inhibitor of phosphodiesterase V (PDE 5), a potent coronary vasodilator drug, an adenosine transport inhibitor, and inhibitor of platelet aggregation.

Technology Process of 2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol

There total 1 articles about 2,2',2'',2'''-((4-((2-Hydroxyethyl)amino)-8-(piperidin-1-yl)pyrimido(5,4-d)pyrimidine-2,6-diyl)dinitrilo)tetraethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: