(3S)-N¹-(4-chlorobenzyl)-4-oxo-4-(piperidin-1-yl)butane-1,3-diamine dihydrochloride

Base Information

• Chemical Name: (3S)-N¹-(4-chlorobenzyl)-4-oxo-4-(piperidin-1-yl)butane-1,3-diamine dihydrochloride
• CAS No.: 697797-51-6
• Molecular Formula: C₁₆H₂₄ClN₃O*2ClH
• Molecular Weight: 382.761
• Mol file: 697797-51-6.mol

Synonyms:

Chemical Property of (3S)-N¹-(4-chlorobenzyl)-4-oxo-4-(piperidin-1-yl)butane-1,3-diamine dihydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

UAMC00039Dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: UAMC 0039 is a potent inhibitor of dipeptidyl peptidase 2 (DPP-2; IC50 = 0.48 nM). It also inhibits DPP-4 (IC50 = 165 μM). DPP-2 is thought to be involved in degradation of collagen, substance P, and some proline-containing neuropeptides.
• Uses: UAMC 00039 Dihydrochloride is a highly potent and selective dipeptidase II inhibitor.

Technology Process of (3S)-N¹-(4-chlorobenzyl)-4-oxo-4-(piperidin-1-yl)butane-1,3-diamine dihydrochloride

There total 1 articles about (3S)-N¹-(4-chlorobenzyl)-4-oxo-4-(piperidin-1-yl)butane-1,3-diamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyl [(S)-4-((4-chlorobenzyl)amino)-1-oxo-1-(piperidin-1-yl)butan-2-yl]carbamate (1011735-56-0) → (3S)-N1-(4-chlorobenzyl)-4-oxo-4-(piperidin-1-yl)butane-1,3-diamine dihydrochloride (697797-51-6)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃;

DOI:10.1080/00397910701693633

upstream raw materials:

tert-butyl [(S)-4-((4-chlorobenzyl)amino)-1-oxo-1-(piperidin-1-yl)butan-2-yl]carbamate