ethyl 10b-hydroxy-3,6-dioxo-2,5-di(propan-2-yl)octahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylate

Base Information

• Chemical Name: ethyl 10b-hydroxy-3,6-dioxo-2,5-di(propan-2-yl)octahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylate
• CAS No.: 60828-46-8
• Molecular Formula: C₁₈H₂₈N₂O₆
• Molecular Weight: 368.43
• NSC Number: 196865,179493
• DSSTox Substance ID: DTXSID80306734
• Mol file: 60828-46-8.mol

Synonyms:60828-46-8;NSC179493;SCHEMBL11867395;DTXSID80306734;NSC196865;NSC-179493;NSC-196865;ethyl 10b-hydroxy-3,6-dioxo-2,5-di(propan-2-yl)octahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylate

Chemical Property of ethyl 10b-hydroxy-3,6-dioxo-2,5-di(propan-2-yl)octahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylate

Chemical Property:

• Vapor Pressure: 1.19E-13mmHg at 25°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 368.19473662
• Heavy Atom Count: 26
• Complexity: 635

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)C1(C(=O)N2C(C(=O)N3CCCC3C2(O1)O)C(C)C)C(C)C

Technology Process of ethyl 10b-hydroxy-3,6-dioxo-2,5-di(propan-2-yl)octahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylate

There total 3 articles about ethyl 10b-hydroxy-3,6-dioxo-2,5-di(propan-2-yl)octahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Cyclol-carbonsaeure-ethylester (24177-14-8,60828-46-8)

Guidance literature:

(S)-(+)-Isopropyl-benzyloxy-malonesterchlorid, Val-OBzl;

DOI:10.1007/BF00906783

Reference yield:

→ 10b-hydroxy-2,5-diisopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine-2-carboxylic acid ethyl ester (24177-14-8,60828-46-8)

Guidance literature:

12, H2, Pd-C (10percent), neben 13a;

Reference yield:

→ 2-Ethoxycarbonyl-2,5-diisopropyl-10b-hydroxy-3,6-dioxo-octahydro-8H-oxazolo<3,2-a>pyrrolo<2,1-c>pyrazin (24177-14-8,60828-46-8)

Guidance literature:

(2R-2-Hydroxy-2-ethoxycarbonyl-isovaleryl)-Val-Pro-ONP, NaH (NP=p-Nitrophenyl);

Refernces