4-Butyl-1,3-oxazolidine-2,5-dione

Base Information

• Chemical Name: 4-Butyl-1,3-oxazolidine-2,5-dione
• CAS No.: 29774-91-2
• Molecular Formula: C₇H₁₁NO₃
• Molecular Weight: 157.169
• NSC Number: 36205
• DSSTox Substance ID: DTXSID70284198,DTXSID601309223
• Mol file: 29774-91-2.mol

Synonyms:4-butyloxazolidine-2,5-dione;29774-91-2;4-butyl-1,3-oxazolidine-2,5-dione;6271-01-8;NSC36205;4-Butyl-2,5-oxazolidinedione;SCHEMBL7659302;DTXSID70284198;DTXSID601309223;AC8929;MFCD24550243;MFCD31630315;NSC-36205;SY225146;SY225304;A919314

Chemical Property of 4-Butyl-1,3-oxazolidine-2,5-dione

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 157.07389321
• Heavy Atom Count: 11
• Complexity: 179

Purity/Quality:

97% ^*data from raw suppliers

4-Butyl-1,3-oxazolidine-2,5-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCC1C(=O)OC(=O)N1

Technology Process of 4-Butyl-1,3-oxazolidine-2,5-dione

There total 4 articles about 4-Butyl-1,3-oxazolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-butyl-oxazolidine-2,5-dione (29774-91-2,6271-01-8,29774-90-1)

Guidance literature:

With thionyl chloride;

Reference yield:

N-benzyloxycarbonylnorleucine (15027-13-1) → 4-butyl-oxazolidine-2,5-dione (29774-91-2,6271-01-8,29774-90-1)

Guidance literature:

With diethyl ether; phosphorus pentachloride;

Reference yield:

2-amino-hexanoic acid (616-06-8) → 4-butyl-oxazolidine-2,5-dione (29774-91-2,6271-01-8,29774-90-1)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorocarbonic acid benzyl ester; aqueous NaOH

2: PCl₅; diethyl ether

With sodium hydroxide; diethyl ether; phosphorus pentachloride; benzyl chloroformate;

upstream raw materials:

phosgene

2-amino-hexanoic acid

N-benzyloxycarbonylnorleucine