trans-4,5-Dihydroxy-4,5-dihydrobenzopyren

Base Information

• Chemical Name: trans-4,5-Dihydroxy-4,5-dihydrobenzopyren
• CAS No.: 146863-60-7
• Molecular Formula: C₂₀H₁₄O₂
• Molecular Weight: 286.33
• Mol file: 146863-60-7.mol

Synonyms:

Chemical Property of trans-4,5-Dihydroxy-4,5-dihydrobenzopyren

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-4,5-Dihydroxy-4,5-dihydrobenzopyren

There total 3 articles about trans-4,5-Dihydroxy-4,5-dihydrobenzopyren which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzopyrene-4,5-dione (66788-08-7) → trans-4,5-Dihydroxy-4,5-dihydrobenzopyren (24909-10-2,24961-49-7,66788-09-8,146863-59-4,146863-60-7)

Guidance literature:

With sodium tetrahydroborate; oxygen; In ethanol; for 24h; Ambient temperature;

DOI:10.1055/s-1982-29834

Reference yield:

benzo[e]pyrene (192-97-2) → trans-4,5-Dihydroxy-4,5-dihydrobenzopyren (24909-10-2,24961-49-7,66788-09-8,146863-59-4,146863-60-7)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) OsO₄, Py, (ii) aq. NaHSO₃, Py

2: DDQ

3: KBH₄

With potassium borohydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone;

DOI:10.1021/jo00412a008

Reference yield:

cis-4,5-Dihydroxy-4,5-dihydrobenzopyrene (24909-10-2) → trans-4,5-Dihydroxy-4,5-dihydrobenzopyren (24909-10-2,24961-49-7,66788-09-8,146863-59-4,146863-60-7)

Guidance literature:

Multi-step reaction with 2 steps

1: DDQ

2: KBH₄

With potassium borohydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone;

DOI:10.1021/jo00412a008

upstream raw materials:

benzopyrene-4,5-dione

benzo[e]pyrene

cis-4,5-Dihydroxy-4,5-dihydrobenzopyrene