6'-sialyl-N-acetyllactosamine

Base Information

Chemical Name:6'-sialyl-N-acetyllactosamine
CAS No.:89824-83-9
Molecular Formula:C₂₅H₄₂N₂O₁₉
Molecular Weight:674.61
Hs Code.:

Synonyms:

Suppliers and Price of 6'-sialyl-N-acetyllactosamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6'-sialyl-N-acetyllactosamine

Chemical Property:

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Technology Process of 6'-sialyl-N-acetyllactosamine

There total 29 articles about 6'-sialyl-N-acetyllactosamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 89733-66-4
Benzyl-O-(5-acetamido-3,5-didesoxy-D-glycero-β-D-galacto-2-nonulopyranosylonsaeure)-(2->6)-O-(2,3-di-O-benzyl-β-D-galactopyranosyl)-(1->4)-2-acetamido-3,6-di-O-benzyl-2-desoxy-β-D-glucopyranosid

: 17048-95-2,64364-50-7,89824-82-8,89824-83-9
6'-sialyl-N-acetyllactosamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In 1,4-dioxane; methanol; for 16h; Ambient temperature;
DOI:10.1016/0008-6215(84)85141-1

Reference yield: 64.3%

: 4307-58-8,6050-69-7,30868-22-5,34641-68-4,36954-65-1,47491-70-3,58718-18-6,60966-24-7,62929-48-0,69610-06-6,71698-59-4,75917-82-7,87982-93-2,87982-94-3,93601-71-9,109121-51-9,135760-02-0
N-acetyl-D-lactosamine

: CMP-Neu₅Ac

: 17048-95-2,64364-50-7,89824-82-8,89824-83-9
Neu5Acα2,6Galβ1,4GlcNAc

Guidance literature:: at 37 ℃; for 24h; α-2,6-sialyltransferase, BSA;
DOI:10.1021/ja953495e

Reference yield:

: 19342-36-0
2,4,7,8,9-Penta-O-acetyl-N-acetyl-β-D-neuraminsaeure

: 17048-95-2,64364-50-7,89824-82-8,89824-83-9
6'-sialyl-N-acetyllactosamine

Guidance literature:: Multi-step reaction with 7 steps

1: diethyl ether; methanol

2: 94 percent / TiCl₄ / CH₂Cl₂; ethyl acetate / 0 deg C 16 hour, room temp. 5 hour.

3: 23 percent / Hg(CN)2, HgBr₂ / CH₂Cl₂ / 120 h / Ambient temperature

4: 75 percent / H₂S / pyridine; H₂O

5: 75 percent / Pyridin / 24 h

6: 94 percent / NaOMe / methanol / 4 h / Ambient temperature

7: 93 percent / H₂ / Pd/C / methanol; dioxane / 16 h / Ambient temperature

With pyridine; hydrogen sulfide; hydrogen; sodium methylate; mercury(II) cyanide; titanium tetrachloride; mercury dibromide; palladium on activated charcoal; In 1,4-dioxane; pyridine; methanol; diethyl ether; dichloromethane; water; ethyl acetate;
DOI:10.1016/0008-6215(84)85141-1