Technology Process of sodium 3,4-dihydroxy-1,3,5(10)-estatrien-17-one 4-sulfate
There total 4 articles about sodium 3,4-dihydroxy-1,3,5(10)-estatrien-17-one 4-sulfate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
for 20h;
Yield given;
DOI:10.1248/cpb.30.4417
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 380 mg / NaNO2, 22percent H2SO4 / H2O / 1.) ice-cooling, 1 h; 2.) reflux, 40 min
2: sulfur trioxide-pyridine complex / pyridine / 12 h / ice-cooling
3: H2 / 5percent Pd-C / methanol / 20 h
With
sulfuric acid; hydrogen; sulfur trioxide pyridine complex; sodium nitrite;
palladium on activated charcoal;
In
pyridine; methanol; water;
DOI:10.1248/cpb.30.4417
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sulfur trioxide-pyridine complex / pyridine / 12 h / ice-cooling
2: H2 / 5percent Pd-C / methanol / 20 h
With
hydrogen; sulfur trioxide pyridine complex;
palladium on activated charcoal;
In
pyridine; methanol;
DOI:10.1248/cpb.30.4417
