N-[4-(tert-butylamino)phenyl]acetamide

Base Information

• Chemical Name: N-[4-(tert-butylamino)phenyl]acetamide
• CAS No.: 61015-96-1
• Molecular Formula: C₁₂H₁₈N₂O
• Molecular Weight: 206.288
• Mol file: 61015-96-1.mol

Synonyms:

Chemical Property of N-[4-(tert-butylamino)phenyl]acetamide

Chemical Property:

• Storage Temp.: 2-8°C

Purity/Quality:

N-(4-(tert-butylamino)phenyl) acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

Technology Process of N-[4-(tert-butylamino)phenyl]acetamide

There total 1 articles about N-[4-(tert-butylamino)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-tert.Butyl-N'-acetyl-p-phenylendiamin (61015-96-1)

Guidance literature:

With potassium carbonate; In water; acetone; at 50 ℃; for 2h;

Refernces