Technology Process of 1-benzyl-2-[4-(benzyloxy)phenyl]-5-oxo-2-pyrrolidinecarbonitrile
There total 4 articles about 1-benzyl-2-[4-(benzyloxy)phenyl]-5-oxo-2-pyrrolidinecarbonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate;
In
acetonitrile;
at 45 - 50 ℃;
for 4h;
DOI:10.1007/s00044-016-1731-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: acetic acid / ethanol; water / 0.17 h / 20 °C
1.2: 20 °C
2.1: potassium carbonate / 1,2-dichloro-ethane / 10 - 45 °C
3.1: potassium carbonate; N-benzyl-N,N,N-triethylammonium chloride / acetonitrile / 4 h / 45 - 50 °C
With
N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; acetic acid;
In
ethanol; water; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1007/s00044-016-1731-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: acetic acid / ethanol; water / 0.17 h / 20 °C
1.2: 20 °C
2.1: potassium carbonate / 1,2-dichloro-ethane / 10 - 45 °C
3.1: potassium carbonate; N-benzyl-N,N,N-triethylammonium chloride / acetonitrile / 4 h / 45 - 50 °C
With
N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate; acetic acid;
In
ethanol; water; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1007/s00044-016-1731-7
